Cardiovascular outcomes trials with non-statin lipid-lowering drugs in diabetes
نویسندگان
چکیده
منابع مشابه
Cardiometabolic impact of non-statin lipid lowering therapies.
Among the range of lipid modifying medications currently available, statins clearly stand as the primary agent capable of reducing cardiovascular risk. While non-statin lipid-lowering drugs improve lipid parameters, their impact on clinical outcomes is less clear, thus necessitating an even closer look at ancillary effects. Recent studies have reported the potential cardiometabolic effects of s...
متن کاملGlycaemic Effects of Non-statin Lipid-Lowering Therapies
Since the publication of the JUPITER trial, attention has been focused on the adverse glycemic effects of statin therapy. Although the modest increase in the risk of new diabetes mellitus is outweighed by the reduction in cardiovascular events for statins, emerging biochemical and genetic links between lipid metabolism and glycemic control raise the prospect of a broader diabetogenic effect of ...
متن کاملLipid lowering drugs.
likelv that L donovani was of animal origin, as were other members of the genus, and in Brazil, foxes are a significant animal reservoir. The sensitivity of the Brazilian disease to antimonial drugs does not fit with the resistance of the infantum subspecies found in Portugal. Today there are epidemics of kala-azar among poor children in favelas in cities of north eastern Brazil such as Teresin...
متن کاملIntensive lipid lowering by statin therapy does not improve vasoreactivity in patients with type 2 diabetes.
Cardiovascular disease is the most important cause of morbidity and mortality in patients with type 2 diabetes. Endothelial dysfunction predicts cardiovascular outcome. Type 2 diabetes is characterized by endothelial dysfunction, which may be caused by dyslipidemia. Statin therapy restores endothelial function in hyperlipidemic patients. Therefore, we hypothesize a beneficial effect of atorvast...
متن کاملSevere irritability associated with statin cholesterol-lowering drugs.
BACKGROUND As use of a drug becomes widespread, the full spectrum of its effects becomes clearer. Although a link has been suggested between low or lowered cholesterol and irritability/aggression, less is known about possible links between irritability and statins. AIM To assess the possible connection of statin usage to severe irritability. DESIGN Case series. METHODS Six patients referr...
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ژورنال
عنوان ژورنال: British Journal of Diabetes
سال: 2018
ISSN: 2397-6241,2397-6233
DOI: 10.15277/bjd.2018.180